HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyrimidine → HCID 23726022, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | HCID 178432460 | HCID 178432460 | — |
| Product | HCID 23726022 | HCID 23726022 | 48% |
Reaction Steps
As described for Example 57, 5-methyl-4-(2-methyl-1H-imidazol-4-yl)-3-phenyl-isoxazole (70 mg, 0.3 mmol) using 2-chloropyrimidine instead of 4-fluoroacetophenone was converted to the title compound (45 mg, 48%) which was obtained as a white solid. MS: m/e=318.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-814aa7996de44c19b3f94bfc71a47ceb |
| Source note | uspto-grants-2008_08 |