HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromoacetyl)-5-methyl-3-phenylisoxazole → HCID 178434977, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromoacetyl)-5-methyl-3-phenylisoxazole | HCID 2735531 | — |
| Reactant | Cyclopropanecarboximidamide hydrochloride | HCID 2781916 | — |
| Product | HCID 178434977 | HCID 178434977 | 85% |
Reaction Steps
As described for Example 57, 4-(bromoacetyl)-5-methyl-3-phenylisoxazole (commercially available) (1.5 g, 5 mmol) using cycloproylcarbamidine HCl instead of acetamidine HCl was converted to the title compound (1.2 g, 85%) which was obtained as an off-white solid. MS: m/e=266.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-49e8c527b7104cb19aa0fba5e9e3fe8d |
| Source note | uspto-grants-2008_08 |