HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzonitrile → HCID 23725385, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzonitrile | HCID 14517 | — |
| Reactant | HCID 178434979 | HCID 178434979 | — |
| Product | HCID 23725385 | HCID 23725385 | 82% |
Reaction Steps
As described for Example 63, 4-(2-benzyloxymethyl-1H-imidazol-4-yl)-5-methyl-3-phenyl-isoxazole (100 mg, 0.29 mmol) using 4-fluorobenzonitrile instead of 4-fluoroacetophenone was converted to the title compound (106 mg, 82%) which was obtained as a white foam. MS: m/e=447.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-a5c4036aace544a19c70caac41eacf0c |
| Source note | uspto-grants-2008_08 |