HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyrimidine → HCID 23726023, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | HCID 178434979 | HCID 178434979 | — |
| Product | HCID 23726023 | HCID 23726023 | 41% |
Reaction Steps
As described for Example 63, 4-(2-benzyloxymethyl-1H-imidazol-4-yl)-5-methyl-3-phenyl-isoxazole (60 mg, 0.17 mmol) using 2-chloropyrimidine instead of 4-fluoroacetophenone was converted to the title compound (30 mg, 41%) which was obtained as an off-white solid. MS: m/e=424.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-7d82277d26f942338a872695f3ba5303 |
| Source note | uspto-grants-2008_08 |