4-Aminotetrahydropyran → HCID 67420018, compound

Participants

Reaction Steps

As described for Example 71c, 4-[4-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazol-1-yl]-benzoic acid (100 mg, 0.29 mmol) was converted, using tetrahydro-pyran-4-ylamine instead of cyclopropylmethylamine, to the title compound (16 mg, 13%) which was obtained as an off-white solid. MS: m/e=428.9 [M+H]+.

Provenance & Evidence