HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-fluoro-4-(trifluoromethyl)- → HCID 86613564, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-fluoro-4-(trifluoromethyl)- | HCID 67873 | — |
| Reactant | HCID 178494752 | HCID 178494752 | — |
| Product | HCID 86613564 | HCID 86613564 | 63% |
Reaction Steps
As described for Example 1f, 3-phenyl-4-(1H-imidazol-4-yl)-5-methoxymethyl-isoxazole (127.6 mg, 0.50 mmol) was converted, using 1-fluoro-4-trifluoromethyl-benzene instead of 1-(4-fluorophenyl)-ethanone, to the title compound (125 mg, 63%) which was obtained as an off-white solid. MS: m/e=400.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-bda46ae6f6de44c586baafe8af8d4e28 |
| Source note | uspto-grants-2008_08 |