反应详情

As described for Example 140, 3-(4-fluoro-phenyl)-5-methoxymethyl-4-[1-(4-trifluoromethyl-phenyl)-1H-imidazol-4-yl]-isoxazole (417 mg, 1.13 mmol), instead of 1-(4-{4-[3-(4-fluoro-phenyl)-5-methoxymethyl-isoxazol-4-yl]-imidazol-1-yl}-phenyl)-ethanone, was converted to the title compound (460 mg, 95%) which was obtained as yellow solid. MS: m/e=403.9 [M+H]+.