2-Fluorobenzylic alcohol → HCID 23725640, compound

Participants

Reaction Steps

As described for Example 157, 4-[2-chloromethyl-1-(4-nitro-phenyl)-1H-imidazol-4-yl]-5-methyl-3-phenyl-isoxazole (100 mg, 0.25 mmol), using 2-fluorobenzyl alcohol instead of 3-chlorobenzyl alcohol, was converted to the title compound (75 mg, 61%) which was obtained as a light yellow foam. MS: m/e=485.5 [M+H]+.

Provenance & Evidence