3,5-Difluoropyridine → HCID 11530493, compound

HRID 2219481Notes

Reaction equation

HRID 2219481 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:9][C:10]([C:12]2[C:17]([NH2:18])=[CH:16][CH:15]=[C:14]([CH3:19])[N:13]=2)=[O:11])=[N:6][C:7]=1[CH3:8].[F:20][C:21]1[CH:22]=[N:23][CH:24]=[C:25](F)[CH:26]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:9][C:10]([C:12]2[C:17]([NH:18][C:25]3[CH:24]=[N:23][CH:22]=[C:21]([F:20])[CH:26]=3)=[CH:16][CH:15]=[C:14]([CH3:19])[N:13]=2)=[O:11])=[N:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 6428203,5-DifluoropyridineHCID 86607570HCID 86607570, compound

Product 1

HCID 11530493HCID 11530493, compound

Procedure

The title compound, light yellow solid, MS (ISP): m/e=356.1 (M+H+), was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (5-fluoro-6-methyl-pyridin-2-yl)-amide and 3,5-Difluoropyridine in accordance with the general method of example 7.

Sources & evidence

ORD record
ord-921d4001539c4100b62a8f0be1e82f5a
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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