3-Bromobenzonitrile → HCID 86607577, compound

HRID 2219492Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[C:6]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])[CH:5]=[CH:4][N:3]=1.Br[C:26]1C=C(C=C[CH:33]=1)C#N>>[CH3:1][C:2]1[CH:7]=[C:6]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=[CH:33][CH:26]=[C:22]([C:21]#[N:20])[CH:23]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])[CH:5]=[CH:4][N:3]=1

Participants

Reactant 2

HCID 233813-Bromobenzonitrile

HCID 11522606HCID 11522606, compound

Product 1

HCID 86607577HCID 86607577, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (2-methyl-pyridin-4-yl)-amide (example 5) in accordance with the general method of example 20 using 3-Brombenzonitrile instead of 3-Bromo-4-methylpyridine to yield the final compound as a yellow crystalline solid, MS (ISP): m/e=344.0 (M+H+).

Sources & evidence

ORD record: ord-c87504f1e2424f4cb3761a57e6e87661
Source dataset: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07414060B2

Reaction notes

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