3-Bromo-4-methylpyridine → HCID 86607579, compound

HRID 2219494Notes

Reaction equation

HRID 2219494 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])=[N:6][CH:7]=1.Br[C:26]1C=NC=CC=1C>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=[N:20][CH:21]=[CH:22][C:23]=3[CH3:26])=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 8176303-Bromo-4-methylpyridineHCID 11602237HCID 11602237, compound

Product 1

HCID 86607579HCID 86607579, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (5-fluoro-pyridin-2-yl)-amide (example 8) in accordance with the general method of example 5, step 6 using 3-Bromo-4-methylpyridine instead of 3-Bromopyridine to yield the final compound as a light yellow crystalline solid, MS (ISP): m/e=338.3 (M+H+).

Sources & evidence

ORD record
ord-0486e44ce6484e2aa48cb8f78e826734
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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