3-Bromo-2-methylpyridine → HCID 11580858, compound

HRID 2219495Notes

Reaction equation

HRID 2219495 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])=[N:6][CH:7]=1.Br[C:26]1C(C)=NC=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[C:19]([CH3:26])=[N:20][CH:21]=[CH:22][CH:23]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 12010033-Bromo-2-methylpyridineHCID 11602237HCID 11602237, compound

Product 1

HCID 11580858HCID 11580858, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (5-fluoro-pyridin-2-yl)-amide (example 8) in accordance with the general method of example 20 using 3-Bromo-2-methylpyridine instead of 3-Bromo-4-methylpyridine to yield the final compound as a light yellow crystalline solid, MS (ISP): m/e=338.3 (M+H+).

Sources & evidence

ORD record
ord-e6f5394d9b9c4cfcaa180e2f7ad036e4
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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