HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-oxocyclopentanecarboxylate → 2-(4-Cyclohexyl-phenoxymethyl)-1,2,7,8-tetrahydro-6H-3-oxa-4,8b-diaza-as-indacen-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-oxocyclopentanecarboxylate | HCID 69136 | — |
| Reactant | (S)-5-(4-cyclohexyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine | HCID 66875140 | — |
| Product | 2-(4-Cyclohexyl-phenoxymethyl)-1,2,7,8-tetrahydro-6H-3-oxa-4,8b-diaza-as-indacen-5-one | HCID 44199414 | — |
Reaction Steps
The title compound was prepared from (S)-5-(4-cyclohexyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine and 2-oxo-cyclopentanecarboxylic acid ethyl ester in accordance with the procedures of O.-S. Adetchessi, et. al., Tetrahedron, 61, (2005), 4453-4460. C22H26N2O3 (366.19), LCMS (ESI): 367.16 (M++H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08207181B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-8d297a2b37304c82b6279c2c360b9cd4 |
| Source note | uspto-grants-2012_06 |