3-Bromobenzonitrile → HCID 11653186, compound

HRID 2219507Notes

Reaction equation

HRID 2219507 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH:7][C:8]([C:10]2[C:15]([NH:16][C:17]3[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=3)=[CH:14][CH:13]=[C:12]([CH3:23])[N:11]=2)=[O:9])[S:5][CH:6]=1.Br[C:25]1C=C(C=C[CH:32]=1)C#N>>[CH3:1][C:2]1[N:3]=[C:4]([NH:7][C:8]([C:10]2[C:15]([NH:16][C:17]3[CH:18]=[CH:32][CH:25]=[C:21]([C:20]#[N:19])[CH:22]=3)=[CH:14][CH:13]=[C:12]([CH3:23])[N:11]=2)=[O:9])[S:5][CH:6]=1

Participants

3

Reactant 2

HCID 233813-BromobenzonitrileHCID 115371406-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide

Product 1

HCID 11653186HCID 11653186, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide (example 14) in accordance with the general method of example 20 using 3-Bromobenzonitrile instead of 3-Bromo-4-methylpyridine to yield the final compound as a yellow solid, MS (ISP): m/e=350.3 (M+H+).

Sources & evidence

ORD record
ord-a02e266877074c698a198ac614b75068
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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