3-Bromo-4-methylpyridine → HCID 86607582, compound

HRID 2219520Notes

Reaction equation

HRID 2219520 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:9][C:10]([C:12]2[C:17]([NH:18][C:19]3[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=3)=[CH:16][CH:15]=[C:14]([CH3:25])[N:13]=2)=[O:11])=[N:6][C:7]=1[CH3:8].Br[C:27]1C=NC=CC=1C>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:9][C:10]([C:12]2[C:17]([NH:18][C:19]3[CH:20]=[N:21][CH:22]=[CH:23][C:24]=3[CH3:27])=[CH:16][CH:15]=[C:14]([CH3:25])[N:13]=2)=[O:11])=[N:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 8176303-Bromo-4-methylpyridineHCID 11530141HCID 11530141, compound

Product 1

HCID 86607582HCID 86607582, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (5-fluoro-6-methyl-pyridin-2-yl)-amide (example 11) and 3-Bromo-4-methylpyridine in accordance with the general method of example 20 to yield the final compound as a light yellow crystalline solid, MS (ISP): m/e=352.0 (M+H+).

Sources & evidence

ORD record
ord-05b68cb9c63143e5b46ab5b3beb61a1b
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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