3-Bromo-5-fluoropyridine → HCID 11493913, compound

HRID 2219532Notes

Reaction equation

HRID 2219532 reaction equation
[CH3:1][C:2]1[S:3][CH:4]=[C:5]([NH:7][C:8]([C:10]2[C:15]([NH2:16])=[CH:14][CH:13]=[C:12]([CH3:17])[N:11]=2)=[O:9])[N:6]=1.Br[C:19]1[CH:20]=[N:21][CH:22]=[C:23]([F:25])[CH:24]=1>>[CH3:1][C:2]1[S:3][CH:4]=[C:5]([NH:7][C:8]([C:10]2[C:15]([NH:16][C:19]3[CH:20]=[N:21][CH:22]=[C:23]([F:25])[CH:24]=3)=[CH:14][CH:13]=[C:12]([CH3:17])[N:11]=2)=[O:9])[N:6]=1

Participants

3

Reactant 2

HCID 8202063-Bromo-5-fluoropyridineHCID 86607586HCID 86607586, compound

Product 1

HCID 11493913HCID 11493913, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (2-methyl-thiazol-4-yl)-amide and 3-Bromo-5-fluoropyridine in accordance with the general method of example 20 to yield the final compound as an off-white solid, MS (ISP): m/e=344.3 (M+H+).

Sources & evidence

ORD record
ord-937b4fd0418d4e9c94f099b2a8e0ba89
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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