1-Bromo-3-fluorobenzene → HCID 11610360, compound

HRID 2219538Notes

Reaction equation

HRID 2219538 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([C:13]2[C:18]([NH2:19])=[CH:17][CH:16]=[C:15]([CH3:20])[N:14]=2)=[O:12])=[N:6]1.Br[C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([F:28])[CH:23]=1>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([C:13]2[C:18]([NH:19][C:22]3[CH:27]=[CH:26][CH:25]=[C:24]([F:28])[CH:23]=3)=[CH:17][CH:16]=[C:15]([CH3:20])[N:14]=2)=[O:12])=[N:6]1

Participants

3

Reactant 2

HCID 140821-Bromo-3-fluorobenzeneHCID 86607587HCID 86607587, compound

Product 1

HCID 11610360HCID 11610360, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid [1-(2-methoxy-ethyl)-1H-pyrazol-3-yl]-amide in accordance with the general method of example, step using 1-Bromo-3-fluorobenzene instead of 3-bromopyridineto yield the final compound as a yellow oil, MS (ISP): m/e=370.3 (M+H+).

Sources & evidence

ORD record
ord-e82fe225d21641a59e8ec984e9343cef
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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