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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2219551Generated: November 2, 2026

2-Methyl-2H-pyrazol-3-ylamine → 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide

https://huagongshe.com/reaction/2219551

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-2H-pyrazol-3-ylamineHCID 136927—
Reactant3-Bromo-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amideHCID 86607590—
Product6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amideHCID 11652517—

Reaction Steps

The title compound, was prepared from 3-Bromo-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide in accordance with the general method of Example 78, step 3 using 5-Amino-1-methyl-pyrazole instead of 3-Amino-1-methyl-pyrazole to yield the final compound as a yellow solid, MS (ISP): m/e=312.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07414060B2
Source datasetuspto-grants-2008_08
ORD IDord-83f78fdf61d94bc689449e1d50417d2e
Source noteuspto-grants-2008_08