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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2219557Generated: October 31, 2026

3-Amino-5-chloropyridine → 3-(5-Chloro-pyridin-3-ylamino)-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide

https://huagongshe.com/reaction/2219557

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-5-chloropyridineHCID 818257—
Reactant3-Bromo-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amideHCID 86607590—
Product3-(5-Chloro-pyridin-3-ylamino)-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amideHCID 11580955—

Reaction Steps

The title compound, was prepared from 3-Bromo-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide in accordance with the general method of Example 78, step 3 using 3-Amino-5-chloropyridine instead of 3-Amino-1-methyl-pyrazole to yield the final compound as a yellow solid, MS (ISP): m/e=343.0, 345.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07414060B2
Source datasetuspto-grants-2008_08
ORD IDord-55bc89b28cb646d0a0da17c8a69f93a3
Source noteuspto-grants-2008_08