HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-fluoropyridine → 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid (5-fluoro-pyridin-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-fluoropyridine | HCID 2737701 | — |
| Reactant | 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid ethyl ester | HCID 69237299 | — |
| Product | 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid (5-fluoro-pyridin-2-yl)-amide | HCID 86607591 | — |
Reaction Steps
The title compound, was prepared from 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid ethyl ester and 2-Amino-5-fluoropyridine in accordance with the general method of Example 78, step 2 to yield the final compound as a yellow crystalline solid, MS (ISP): m/e=327.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-2318f5cc53d3417a86eb4e28183b6ef6 |
| Source note | uspto-grants-2008_08 |