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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2219564Generated: November 2, 2026

2-Amino-4-methylthiazole → 3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide

https://huagongshe.com/reaction/2219564

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-methylthiazoleHCID 74143—
Reactant3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid ethyl esterHCID 69236417—
Product3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amideHCID 25097156—

Reaction Steps

The title compound, was prepared in accordance with the general method of Example 78, step 2 from 3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid ethyl ester and 2-Amino-4-methylthiazole to yield the final compound as a yellow solid, MS (ISP): m/e=343.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07414060B2
Source datasetuspto-grants-2008_08
ORD IDord-ff2b36da44db4da0bdbe843bd9a7f508
Source noteuspto-grants-2008_08