HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyridine → 6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | Ethyl 3-bromo-6-methylpicolinate | HCID 69237506 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl ester | HCID 69237214 | — |
Reaction Steps
The Pd catalyzed coupling of 3-Bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester and 3-Amino-pyridine was performed in accordance with the general method of Example 78, step 3 to yield the title compound as a light yellow crystalline solid, MS (ISP): m/e=258.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-f939f373b0384a4788082d4e90acb1c3 |
| Source note | uspto-grants-2008_08 |