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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2219577Generated: November 2, 2026

2-Amino-5-methylthiazole → 6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid (5-methyl-thiazol-2-yl)-amide

https://huagongshe.com/reaction/2219577

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-methylthiazoleHCID 351770—
Reactant6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl esterHCID 69237214—
Product6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid (5-methyl-thiazol-2-yl)-amideHCID 11515352—

Reaction Steps

The title compound, was prepared from 6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl ester and 2-Amino-5-methylthiazole in accordance with the general method of example 78, step 2 to yield the final compound as a yellow crystalline solid, MS (ISP): m/e=326.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07414060B2
Source datasetuspto-grants-2008_08
ORD IDord-fc180224ebb64ea1bf705761317ab125
Source noteuspto-grants-2008_08