HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)benzenesulfonyl chloride → HCID 86604883, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)benzenesulfonyl chloride | HCID 2733250 | — |
| Reactant | 4-Methyl-N-[(1S)-1-methyl-2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]benzenesulfonamide | HCID 13145046 | — |
| Reactant | (S)-2-Amino-2-(4-fluorophenyl)ethanol | HCID 51669578 | — |
| Product | HCID 86604883 | HCID 86604883 | — |
Reaction Steps
Proceeding as described for (45), but using (S)-2-amino-2-(4-fluorophenyl)ethanol and 3-trifluoromethylbenzenesulfonyl chloride afforded (S)-2-(4-fluorophenyl)-2-(3-(trifluoro-methyl)benzenesulfonamido)ethyl 3-(trifluoromethyl)benzenesulfonate (47). MS m/z: 572.3 (M+H) (Calc'd for C22H16F7NO5S2: 571.48).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414134B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-98d33cbc225c44439b9ca54cbdf63453 |
| Source note | uspto-grants-2008_08 |