HCID 59771820, compound → HCID 59771821, compound

Participants

Reaction Steps

To a stirred solution of (R)-3-(1-((R)-6-(hydroxymethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-1H-1,2,3-triazol-4-yl)-2-(4-methylbenzenesulfonamido)propanamide (0.66 g, 1.4 mmol) in DCE/MeCN (1:1, 30 mL) was added MnO2. The reaction mixture was stirred overnight at RT. The solid was removed by filtration, and the filtrate was concentrated to give a tan solid. MS (m/z): 468.4 (m+H).

Provenance & Evidence