Potassium Carbonate → HCID 86602787, compound

Participants

Reaction Steps

0.08 g 4-methoxycyclohexanol, 0.16 g triphenylphosphine and 0.12 ml diisopropyl azodicarboxylate are added to a solution of 0.25 g 1-chloro-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-2-hydroxy-benzene in 3 ml of tetrahydrofuran, in the order stated. The solution is stirred for 14 h at ambient temperature and then combined with aqueous potassium carbonate solution. Then it is extracted with ethyl acetate, dried over sodium sulphate and the solvent is removed. The residue is purified on silica gel (cyclohexane/ethyl acetate 7:3->1:1).

Provenance & Evidence