HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloromethyl tetrahydrofuran → 4-(3-Methanesulfonyl-phenyl)-1-(tetrahydrofuran-2-ylmethyl)-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloromethyl tetrahydrofuran | HCID 18150 | — |
| Reactant | 4-(3-(Methylsulfonyl)phenyl)piperidine | HCID 12988957 | — |
| Product | 4-(3-Methanesulfonyl-phenyl)-1-(tetrahydrofuran-2-ylmethyl)-piperidine | HCID 22397845 | — |
Reaction Steps
Beginning with 4-(3-methanesulfonyl-phenyl)piperidine and tetrahydrofurfuryl chloride, the titled compound was recovered by the procedure described in Example 1. MS m/z (relative intensity, 70 eV) 323 (M+, 1), 252 (bp), 129 (9), 115 (6), 70 (17). Rf=0.3 (MeOH, 0.03 (EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417043B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-fa93495c78444ff0aee8e9619dcbba7c |
| Source note | uspto-grants-2008_08 |