2-(Tributylstannyl)-1,3-benzothiazole → HCID 10308926, compound

HRID 2220122Notes

Reaction equation

HRID 2220122 reaction equation
Br[C:2]1[CH:3]=[C:4]2[CH2:10][C@:9]3([CH:15]4[CH2:16][CH2:17][N:12]([CH2:13][CH2:14]4)[CH2:11]3)[O:8][C:5]2=[N:6][CH:7]=1.C([Sn](CCCC)(CCCC)[C:23]1[S:24][C:25]2[CH:31]=[CH:30][CH:29]=[CH:28][C:26]=2[N:27]=1)CCC>>[S:24]1[C:25]2[CH:31]=[CH:30][CH:29]=[CH:28][C:26]=2[N:27]=[C:23]1[C:2]1[CH:3]=[C:4]2[CH2:10][C@:9]3([CH:15]4[CH2:16][CH2:17][N:12]([CH2:13][CH2:14]4)[CH2:11]3)[O:8][C:5]2=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 37623922-(Tributylstannyl)-1,3-benzothiazoleHCID 54506690(2R)-5'-bromo-3'H-spiro[4-azabicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine]

Product 1

HCID 10308926HCID 10308926, compound

Procedure

Prepared by a method analogous to that described for the preparation of Example 1 from (2′R)-5′-bromospiro[1-azabicyclo[2.2.2]octane-3,2′(3′H)-furo[2,3-b]pyridine] and 2-tri-n-butylstannylbenzothiazole. The title compound was obtained as a colourless solid; m/e 350 (MH+).

Workup

  1. customPrepared by a method analogous to

Sources & evidence

ORD record
ord-1d04a7210d234e36b0d749ffb540fa25
Source dataset
uspto-grants-2008_08
Patent number
US07417050B2

Reaction notes

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