HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 6-[N-(2,4-difluorophenyl)sulfamoyl]-1-cyclohexene-1-carboxylate → Ethyl 6-[(2-chloro4-fluorobenzyl)sulfanyl]-1-cyclohexene-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 6-[N-(2,4-difluorophenyl)sulfamoyl]-1-cyclohexene-1-carboxylate | HCID 9928140 | — |
| Reactant | (2-chloro-4-fluorophenyl)methanethiol | HCID 22026132 | — |
| Product | Ethyl 6-[(2-chloro4-fluorobenzyl)sulfanyl]-1-cyclohexene-1-carboxylate | HCID 22026131 | 78.6% |
Reaction Steps
In the same manner as in Reference Example 1, ethyl 6-[N-(2,4-difluorophenyl)sulfamoyl]-1-cyclohexene-1-carboxylate (835 mg) and (2-chloro-4-fluorophenyl)-methanethiol (853 mg) were reacted to give ethyl 6-[(2-chloro-4-fluorobenzyl)sulfanyl]-1-cyclohexene-1-carboxylate (625 mg) as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417059B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-bcf14c16ca66492fb05ced42554bfb63 |
| Source note | uspto-grants-2008_08 |