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HRID2220242

反应详情

EQUATION

反应方程式

HRID 2220242 的结构方程式

REACTANTS

反应物

4
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：Cc1nccc2c(N)cccc12
HCID9989490

1-methylisoquinolin-5-amine

C10H10N2

结构：CC(C)(CC(O)(C=O)C(F)(F)F)c1cc(F)cc2c1OCC2
HCID44184989

5-Fluoro-2,3-dihydro-α-hydroxy-γ,γ-dimethyl-α-(trifluoromethyl)-7-benzofuranbutanal

C15H16F4O3

结构：Cc1nccc2c(N=CC(O)(CC(C)(C)c3cc(F)cc4c3OCC4)C(F)(F)F)cccc12
HCID68853895

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nccc2c(NCC(O)(CC(C)(C)c3cc(F)cc4c3OCC4)C(F)(F)F)cccc12
HCID11496332

未命名化合物

PROCEDURE

实验过程

Analogously to Example 1, 4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal is converted with 5-amino-1-methylisoquinoline into 5-[4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentylidenamino]-1-methylisoquinoline, which is reduced with sodium borohydride to the product.