HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium cyanoborohydride → HCID 11504215, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | 6-Chloro-2-methylquinolin-5-amine | HCID 15571773 | — |
| Reactant | 4-(2,3-Dihydro-5-fluoro-7-benzofuranyl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal | HCID 44184989 | — |
| Reactant | HCID 68854139 | HCID 68854139 | — |
| Product | HCID 11504215 | HCID 11504215 | — |
Reaction Steps
Analogously to Example 1, 4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal is converted with 5-amino-6-chloro-2-methylquinoline into 5-[4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentylidenamino]-6-chloro-2-methylquinoline, which is reduced with sodium cyanoborohydride to the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417056B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-6a75d41b43cd4be895d3ed900c27f0b7 |
| Source note | uspto-grants-2008_08 |