HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminoisoquinoline → HCID 11575969, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminoisoquinoline | HCID 70766 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 4-(2,3-Dihydro-5-fluoro-7-benzofuranyl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal | HCID 44184989 | — |
| Reactant | HCID 68854135 | HCID 68854135 | — |
| Product | HCID 11575969 | HCID 11575969 | — |
Reaction Steps
Analogously to Example 1, 4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal is converted with 5-aminoisoquinoline into 5-[4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentylidenamino]isoquinoline, which is reduced with sodium borohydride to the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417056B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-3d58d9aaef6440829104b48193215ecf |
| Source note | uspto-grants-2008_08 |