HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → HCID 11989685, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | HCID 11989684 | HCID 11989684 | — |
| Product | HCID 11989685 | HCID 11989685 | 94% |
Reaction Steps
According to Step 4, after reaction of 5-(4-tert-Butylbenzenesulfonylamino)-1-benzothiophene-2-carboxylic acid ethyl ester (5.34 mg, 12.79 mmol) from Example 1b) with N-bromosuccinimide (2.30 g, 12.7 mmol) followed by chromatographic purification (silica gel, hexane/ethyl acetate (0-70% ethyl acetate)), the desired compound is obtained at 94% yield (5.98 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417066B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-7ca6af5bc98b46e192f41d05b58d5a8b |
| Source note | uspto-grants-2008_08 |