HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → HCID 17981923, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 4-Hydroxybenzothiazole | HCID 81901 | — |
| Reactant | 4-Fluoro-7-methoxy-2,3-dihydrobenzo[b]thiophene | HCID 17981921 | — |
| Product | HCID 17981923 | HCID 17981923 | — |
Reaction Steps
A BBr3 demethylation of 4-fluoro-7-methoxy-2,3-dihydrobenzo[b]thiophene similar to that described for 4-hydroxy benzothiazole affords the title compound as a brown solid 251 Mg: δH (300 MHz, CDCl3) 6.57-6.48 (2H, m, ArH), 4.67 (1H, br. s, OH) and 3.43-3.23 (4H, m, SCH2CH2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417064B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-8405399ed8cc4636bb8e96b89e52c3ef |
| Source note | uspto-grants-2008_08 |