[3-(Benzo[b]thiophen-4-yloxy)-5-methyl-hexyl]-benzyl-methyl-amine → [3-(Benzo[b]thiophen-4-yloxy)-hexyl]-benzyl-methyl-amine

HRID 2220355Notes

Reaction equation

HRID 2220355 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[C:6]([O:10][CH:11]([CH2:23][CH:24](C)[CH3:25])[CH2:12][CH2:13][N:14]([CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH3:15])=[CH:7][CH:8]=[CH:9][C:2]1=2.C(N(C)CCC(O)CCC)C1C=CC=CC=1>>[S:1]1[CH:5]=[CH:4][C:3]2[C:6]([O:10][CH:11]([CH2:23][CH2:24][CH3:25])[CH2:12][CH2:13][N:14]([CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH3:15])=[CH:7][CH:8]=[CH:9][C:2]1=2

Participants

3

Reactant 2

HCID 10316919[3-(Benzo[b]thiophen-4-yloxy)-5-methyl-hexyl]-benzyl-methyl-amineHCID 179819281-(Benzyl-methyl-amino)-hexan-3-ol

Product 1

HCID 58591177[3-(Benzo[b]thiophen-4-yloxy)-hexyl]-benzyl-methyl-amine

Procedure

Using a method similar to that for [3-(Benzo[b]thiophen-4-yloxy)-5-methyl-hexyl]-benzyl-methyl-amine, 1-(benzyl-methyl-amino)-hexan-3-ol affords the title compound: mass spectrum (ion spray) m/z=354 (M+1); 1H NMR (CDCl3) δ 7.45-7.41 (m, 2H), 7.29-7.20 (m, 7H), 6.81 (d, 1H), 4.58-4.53 (m, 1H), 3.47 (s, 2H), 2.54 (t, 2H), 2.20 (s, 3H), 2.03-1.90 (m, 2H), 1.88-1.60 (m, 2H), 1.53-1.38 (m, 2H), 0.93 (t, 3H).

Sources & evidence

ORD record
ord-0d56fcbfd37e4e01867c093e0152e784
Source dataset
uspto-grants-2008_08
Patent number
US07417064B2

Reaction notes

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