Hydrochloric Acid → 4-Borono-3-methoxybenzoic acid

Participants

Reaction Steps

Lithium hydroxide monohydrate (0.092 g) was added to a mixture of 4-ethoxycarbonyl-2-methoxyphenylboronic acid (0.049 g), water (1 mL) and 1,4-dioxane (1 mL), and the mixture was stirred at room temperature overnight. To the reaction mixture was added 2 mol/L hydrochloric acid (1.09 mL), and the solvent was evaporated under reduced pressure. The residue was washed with water to afford the title compound (0.035 g).

Provenance & Evidence