Water → HCID 23134133, compound

Participants

Reaction Steps

Methanesulfonyl chloride (0.086 mL) was added to an ice-cooled mixture of benzyl 4′-(2-hydroxyethoxy)biphenyl-4-carboxylate (0.30 g) and triethylamine (0.182 mL) in methylene chloride (20 mL) with stirring, and the mixture was stirred at room temperature for 1 hr. Water and ethyl acetate were added to the reaction mixture. The organic layer was separated, washed with water and brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to afford benzyl 4′-(2-methanesulfonyloxyethoxy)biphenyl-4-carboxylate (0.37 g).

Provenance & Evidence