HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-acetamido-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate → 3-Amino-3,4-dihydroquinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-acetamido-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate | HCID 21853904 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 3-Amino-3,4-dihydroquinolin-2(1H)-one | HCID 13499427 | — |
Reaction Steps
A mixture of 81 in 6 M HCl was refluxed for a time sufficient for reaction completion. After cooling to rt, the mixture was rotary evaporated and dried under vacuum to give 82 as its hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417152B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-9b72bc16c92d42ababcc0f954f7bfd0f |
| Source note | uspto-grants-2008_08 |