HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazole → HCID 59773336, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazole | HCID 1048 | — |
| Reactant | 4-Fluorophenylhydrazine hydrochloride | HCID 69981 | — |
| Reactant | Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylate | HCID 14994510 | — |
| Reactant | 5-Amino-1-tert-butoxycarbonyl-3-methoxycarbonylpyrazole | HCID 59773335 | — |
| Reactant | 4-Methyl-5-(2-chloro-benzoylamino)-1-(pyridine-2-yl)-pyrazole-3-carboxylic acid(2-oxo-5-phenyl-2,3-dihydro-1h-benzo[e][1,4]diazepin-3-yl)amide | HCID 59812227 | — |
| Reactant | HCID 178424381 | HCID 178424381 | — |
| Product | HCID 59773336 | HCID 59773336 | — |
Reaction Steps
The pyrazole acid, prepared as described in Procedure 8 using 5-amino-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid ethyl ester prepared as described for compound 188 in Procedure 41 using 4-fluorophenylhydrazine hydrochloride) in place of compound 20, was coupled to 2-(3,4,5,6-tetrahydro-2H-[1,4′]bipyridin-4-yl)ethylamine (prepared as described in Procedure 14) using the method of Procedure 10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417152B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-60e7487cb5f6407fbeb3dede04d44bdc |
| Source note | uspto-grants-2008_08 |