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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2220785Generated: November 2, 2026

Stearic Acid → HCID 70502183, compound

https://huagongshe.com/reaction/2220785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantStearic AcidHCID 5281—
ReactantBuprenorphine component OF alks-5461HCID 9848990—
ProductHCID 70502183HCID 70502183—

Reaction Steps

Equal amounts of Buprenorphine particles (prepared as described in Example 4) above) and stearic acid (prepared as described in Example 3) were blended and ground. The ground material was compressed in a 13-mm round die, with a force of 5,000 pounds for 5 minutes. Compressed tablets were ground and sieved through a 120-mesh screen followed by a 230-mesh screen to obtain particles having a size range between 63-125 microns.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07368126B2
Source datasetuspto-grants-2008_05
ORD IDord-84004a01edaa4803a8018f5eaee77331
Source noteuspto-grants-2008_05