2-Thiopheneglyoxylic acid → HCID 21083663, compound

HRID 2220879Notes

Reaction equation

HRID 2220879 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([NH2:10])[C:6]([NH2:9])=[CH:7][CH:8]=1)#[N:2].[S:11]1[CH:15]=[CH:14][CH:13]=[C:12]1[C:16](=O)[C:17](O)=[O:18]>>[C:1]([C:3]1[CH:4]=[C:5]2[C:6](=[CH:7][CH:8]=1)[NH:9][C:17](=[O:18])[C:16]([C:12]1[S:11][CH:15]=[CH:14][CH:13]=1)=[N:10]2)#[N:2]

Participants

3

Reactant 2

HCID 776942-Thiopheneglyoxylic acidHCID 7372853,4-Diaminobenzonitrile

Product 1

HCID 21083663HCID 21083663, compound

Procedure

The quinoxalin-2-one of the present example is prepared with 4-cyano-benzene-1,2-diamine and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-cyano-3-thiophen-2-yl-1H-quinoxalin-2-one.

Sources & evidence

ORD record
ord-334e9e0b97a7491ca37f1e19ac34ecaf
Source dataset
uspto-grants-2008_05
Patent number
US07368452B2

Reaction notes

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