Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2220883Generated: October 30, 2026

2-Thiopheneglyoxylic acid → 6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-one

https://huagongshe.com/reaction/2220883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneglyoxylic acidHCID 77694—
Reactant(3,4-Diaminophenyl)methanolHCID 12902832—
Product6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-oneHCID 21083665—

Reaction Steps

The quinoxalin-2-one of the present example is prepared with (3,4-Diamino-phenyl)-methanol and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07368452B2
Source datasetuspto-grants-2008_05
ORD IDord-d0e31cbbf99741b881da2235c458229b
Source noteuspto-grants-2008_05