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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2220885Generated: November 2, 2026

2-Thiopheneglyoxylic acid → 6-Nitro-3-thiophen-2-yl-1H-quinoxalin-2-one

https://huagongshe.com/reaction/2220885

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneglyoxylic acidHCID 77694—
Reactant4-Nitro-1,2-phenylenediamineHCID 5111791—
Product6-Nitro-3-thiophen-2-yl-1H-quinoxalin-2-oneHCID 21083668—

Reaction Steps

The quinoxalin-2-one of the present example is prepared with 4-Nitro-benzene-1,2-diamine and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-Nitro-3-thiophen-2-yl-1H-quinoxalin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07368452B2
Source datasetuspto-grants-2008_05
ORD IDord-b105d53af20548948cf95c3f99762bc4
Source noteuspto-grants-2008_05