Hydroxyamine hydrochloride → HCID 86640247, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-trityl-2,5,6,7-tetrahydro-indazol-4-one (1.32 mmol) in ethanol (5 mL) and pyridine (0.16 mL), hydroxylamine hydrochloride (1.2 eq) was added and the mixture was stirred at 55° C. for 1.5 h. After cooling to rt, the mixture was diluted with water and filtered. The solid was washed with water and dried. Obtained the title compound in 90% yield. ESI (+) MS: m/z 394 (MH+). 1H NMR: 1.69-1.88 (m, 2H), 2.07-2.25 (m, 2H), 2.59-2.67 (m, 1H), 2.77-2.86 (m, 1H), 6.99 (s, 1H), 7.19-7.31 (m, 15H), 9.94 (s, 1H).

Provenance & Evidence