HCID 68705098, compound → HCID 68706384, compound

Participants

Reaction Steps

1-Methyl-1,6-dihydro-1,6,7-triaza-as-indacene-2-carboxylic acid methyl ester D1 (0.67 mmol) was dissolved in 2N sodium hydroxide in MeOH and refluxed for 2.5 h. After solvent removal the slurry was treated with excess 2N hydrochloric acid under vigorous stirring. The precipitate was filtered, washed with water and dried. Obtained the title compound (97%). ESI (+) MS: m/z 216 (MH+); MS (ES−) 214. 1H NMR: 4.35 (s, 3H), 7.30 (d, J=9.75, 1H), 7.34 (s, 1H), 7.58 (d, J=8.90, 1H), 8.49 (s, 1H), 12.61 (bs, 1H), 13.36 (bs, 1H).

Provenance & Evidence