Water → HCID 10297078, compound

Participants

Reaction Steps

The title compound was prepared from 1-[4-(tert-butyl)benzyl]-5-(3-methoxyphenyl)-1H-indole and oxalyl chloride in substantially the same manner, as described in Step 3 of Example 25. The product was obtained as a yellow solid, mp: 86-87° C. Mass spectrum (ESI, [M+H]+) m/z 442. 1HNMR (400 MHz, DMSO-d6): δ 13.50 (br s, 1H), 8.71 (s, 1H), 8.40 (s, 1H), 7.69 (d, 1H, J=8.55 Hz), 7.58 (d, 1H, J=8.55 Hz), 7.40-7.35(m, 3H), 7.24 (d, 2H, J=8.40 Hz), 7.20(d, 1H, J=7.64 Hz), 7.14(s, 1H), 6.93 (d, 1H, J=8.25 Hz), 5.57 (s, 2H), 3.82 (s, 3H), and 1.22 ppm (s, 9H). Elemental Analysis for C28H27NO4.0.1 H2O: Calculated: C, 75.86; H, 6.18; N, 3.16. Found: C, 75.84; H, 5.91; N, 2.98.

Provenance & Evidence