(3-Chlorophenyl)boronic acid → HCID 22032919, compound

Participants

Reaction Steps

The title compound was prepared from 5-bromo-1-[4-(tert-butyl)benzyl]-1H-indole (Step 1 of Example 34) and 3-chlorophenylboronic acid in substantially the same manner, as described in Step 2 of Example 25. The product was obtained as an oil. Mass spectrum (ESI, [M+H]+) m/z 374. 1HNMR (400 MHz, DMSO-d6): δ 7.86 (d, 1H, J=1.53 Hz), 7.68 (dd, 1H, J=1.84 and 1.83 Hz), 7.61 (d, 1H, J=7.79 Hz), 7.43 (d, 1H, J=8.40 Hz), 7.36 (d, 1H, J=8.55 Hz), 7.55-7.54 (m, 2H), 7.46-7.41 (m, 2H), 7.34 (d, 1H, J=1.07 Hz), 7.31 (d, 2H, J=8.40 Hz), 7.13 (d, 2H, J=8.40 Hz), 6.53 (d, 1H, J=3.06 Hz), 5.40 (s, 2H), 1.30 (s, 9H), and 1.21 ppm (s, 9H). Elemental Analysis for C26H27NO: Calculated: C, 84.51; H, 7.37; N, 3.79. Found: C, 85.08; H, 7.35; N, 3.66.

Provenance & Evidence