HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanethiol → N-acetyl-L-methionine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanethiol | HCID 878 | — |
| Reactant | N-(2-oxooxolan-3-yl)acetamide | HCID 325257 | — |
| Product | N-acetyl-L-methionine | HCID 448580 | — |
Reaction Steps
Subsequently the N-acetyl-2-aminobutyrolactone (1 eq) was reacted with various bases in MeSH to give N-acetylmethionine. A mixture of N-acetylaminolactone, base and MeSH (14 eq) was heated in a sealed autoclave. After cooling, expansion and removal of MeSH, the remaining oil was analysed by HPLC. Further details and the yield of N-acetyl-L-methionine achieved are listed in the table below:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07368600B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-3eaa024cf8064eb6ab1f1ef13ef8f70a |
| Source note | uspto-grants-2008_05 |