Ethanol → HCID 23076558, compound

Participants

Reaction Steps

To a solution of 3-bromo-4-{[2-(2-furyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzaldehyde (4.93 g) in tetrahydrofuran (100 mL)-ethanol (50 mL) was gradually added sodium borohydride (0.51 g) at 0° C. After stirring at room temperature for 2 hrs, water was added to the reaction mixture and the precipitated crystals were collected by filtration to give (3-bromo-4-{[2-(2-furyl)-5-methyl-1,3-oxazol-4-yl]methoxy}phenyl)methanol as colorless crystals (4.40 g, yield 89%). Recrystallization from ethyl acetate-hexane gave colorless prism crystals. melting point: 141-142° C.

Provenance & Evidence