HCID 23076431, compound → HCID 69217575, compound

Participants

Reaction Steps

4-[(E)-2-(3-Benzyloxy-1-phenyl-1H-pyrazol-4-yl)ethenyl]-1,3-thiazole (0.81 g), 5% palladium on carbon (0.80 g) and tetrahydrofuran (80 mL) were subjected to catalytic reduction under a hydrogen atmosphere and atmospheric pressure. The catalyst was filtered off and the filtrate was concentrated. The residue was subjected to silica gel column chromatography, and eluted with ethyl acetate-hexane (1:3, v/v) to give 4-[2-(3-benzyloxy-1-phenyl-1H-pyrazol-4-yl)ethyl]-1,3-thiazole as a colorless oil (0.58 g, yield 70%).

Provenance & Evidence